Description

Acetophenone-13C8 is a stable isotope-labeled analog of acetophenone, where all eight carbon atoms are the non-radioactive carbon-13 isotope. This high-purity labeled compound is essential for applications requiring precise internal standards and metabolic pathway tracing in advanced analytical research. It is primarily utilized by analytical laboratories, pharmaceutical R&D departments, and academic institutions engaged in mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and isotope dilution analysis.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference standard in GC-MS and LC-MS analyses for accurate quantification of unlabeled acetophenone in complex matrices.
• Metabolic Pathway Tracing: Used in pharmaceutical and biochemical research to study drug metabolism, degradation pathways, and environmental fate using isotope labeling techniques.
• NMR Spectroscopy Solvent & Reagent: Acts as a chemical shift reference or a labeled starting material in synthetic chemistry for NMR-based structural elucidation and reaction monitoring.
• Isotope Dilution Analysis (IDA): Employed in high-accuracy analytical methods to determine the concentration of acetophenone in environmental, food, or industrial samples.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradants during drug development and quality control.
• Forensic and Doping Control Analysis: Provides a reliable isotopic standard for confirmatory testing in forensic toxicology and anti-doping programs.

Basic Information

Product Name	Acetophenone-13C8
CAS No.	1173022-59-7
Molecular Formula	13C8H8O
Molecular Weight	~108.06 (based on 13C)
Synonyms	1-Phenyl-1-ethanone-13C8; Methyl phenyl ketone-13C8; Phenylethanone-13C8; Acetylbenzene-13C8; Hypnone-13C8; Benzoyl methide-13C8; (13C8)-Acetophenone; APO-13C8
EINECS	Contact for details

Quality Control

Every batch of Acetophenone-13C8 is manufactured and tested under strict quality management systems to ensure exceptional isotopic and chemical purity, consistency, and reliability for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (atom % 13C), chemical purity, and specific analytical results from techniques like NMR, MS, and HPLC. Our quality commitment aligns with the standards expected in pharmaceutical and high-end research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage under optimal conditions, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 13C)	≥ 99%
Chemical Purity (GC/HPLC)	≥ 98%
Specific Rotation (if applicable)	Contact for details
Water Content (KF)	< 0.5%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.