Description

1,3-Difluorobenzene-D4 is a deuterated aromatic compound where four hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This isotopic labeling is critical for applications requiring precise molecular tracking and reduced signal interference in spectroscopic analysis. It is an essential building block and analytical standard for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• NMR Spectroscopy Internal Standard: Serves as a crucial deuterated solvent or reference compound in Nuclear Magnetic Resonance (NMR) analysis due to its specific isotopic pattern.
• Pharmaceutical Research & Development: Used as a labeled intermediate in the synthesis of deuterated drug candidates for metabolic stability studies and pharmacokinetic (PK/PD) research.
• Mass Spectrometry & Analytical Chemistry: Employed as a stable isotope-labeled internal standard for accurate quantification via GC-MS or LC-MS, improving analytical precision.
• Organic Electronics & Material Science: Acts as a precursor for synthesizing deuterated polymers or small molecules, where isotopic substitution can enhance device performance and longevity.
• Agrochemical Development: Utilized in creating labeled versions of pesticides or herbicides to study environmental fate, degradation pathways, and residue analysis.
• Mechanistic Reaction Studies: Provides a valuable tool for elucidating reaction mechanisms in organic chemistry through kinetic isotope effect (KIE) investigations.

Basic Information

Product Name	1,3-Difluorobenzene-D4
CAS No.	1173022-08-6
Molecular Formula	C6D4F2
Molecular Weight	120.12 g/mol
Synonyms	1,3-Difluorobenzene-d4; Deuterated 1,3-Difluorobenzene; [2H4]-1,3-Difluorobenzene; m-Difluorobenzene-d4; Benzene-1,3-difluoro-d4; 1,3-Difluoro-2,4,5,6-tetradeuteriobenzene; Perdeuterated 1,3-Difluorobenzene (common name for fully deuterated form)
EINECS	Contact for details

Quality Control

Every batch of 1,3-Difluorobenzene-D4 is produced and analyzed under strict quality management protocols to ensure isotopic and chemical purity meets the exacting standards of research and industry. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and impurity profiles via validated analytical methods such as NMR, GC-MS, and HPLC. Our quality system supports compliance with cGMP and ISO 9001 standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright away from heat sources and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (D-atom %)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.