Description

Rac Albuterol-D9 CAS NO 1173021-73-2 is a deuterium-labeled isotopologue of the widely used bronchodilator, albuterol (salbutamol). This stable isotope-labeled compound is an essential internal standard for the precise quantification of albuterol in complex biological matrices using advanced analytical techniques like LC-MS/MS. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in pharmacokinetic studies, bioequivalence testing, and drug metabolism research.

Application

• Internal Standard for Bioanalysis: Critical for accurate quantification of albuterol in plasma, serum, and urine samples via mass spectrometry.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion.
• Drug Metabolism and Disposition Research: Used to study metabolic pathways and identify metabolites.
• Bioequivalence Testing: Supports regulatory submissions for generic albuterol formulations by ensuring analytical method accuracy.
• Forensic and Anti-Doping Analysis: Assists in the detection and confirmation of albuterol in forensic toxicology and sports doping control.
• Method Development and Validation: Serves as a key reagent for developing and validating robust, GLP-compliant analytical methods.

Basic Information

Product Name	Rac Albuterol-D9
CAS No.	1173021-73-2
Molecular Formula	C13H12D9NO3
Molecular Weight	242.35 g/mol (approx.)
Synonyms	Racemic Albuterol-d9; (±)-Albuterol-d9; Salbutamol-d9; 2-(tert-Butylamino)-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethanol-d9; 1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(tert-butylamino)ethanol-d9; DL-Albuterol-d9; Ventolin-d9 (labeled analog); Apsomol-d9 (labeled analog)
EINECS	Contact for details

Quality Control

Every batch of Rac Albuterol-D9 is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for sensitive mass spectrometry applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting critical parameters including isotopic purity, chemical purity, and absence of interfering impurities. Our quality commitment supports compliance with GLP and GMP guidelines for research use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.