Description

Guanidineacetic--D2 Acid CAS NO 1173020-63-7 is a deuterated isotopologue of guanidinoacetic acid, a key intermediate in the biosynthesis of creatine. This labeled compound is essential for research and development in metabolic studies, providing a stable, non-radioactive tracer for advanced analytical techniques. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and manufacturers of high-purity biochemicals for applications in mass spectrometry, NMR spectroscopy, and pharmacokinetic research.

Application

• Isotopic Tracer in Metabolic Research: Used as a stable deuterium-labeled internal standard for studying creatine synthesis and metabolism in vivo and in vitro.
• Mass Spectrometry (MS) Standards: Serves as a critical reference standard in LC-MS and GC-MS methods for the accurate quantification of guanidinoacetic acid in biological matrices.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Employed in mechanistic and structural studies due to the distinct NMR signal of the deuterium label.
• Pharmaceutical Development: Used in the research and quality control of drugs targeting energy metabolism, such as those for muscular and neurological disorders.
• Biochemical Synthesis: Acts as a labeled building block for the synthesis of more complex deuterated compounds for research purposes.
• Clinical Diagnostics: Potential use in developing advanced diagnostic assays for metabolic conditions related to creatine deficiency.

Basic Information

Product Name	Guanidineacetic--D2 Acid
CAS No.	1173020-63-7
Molecular Formula	C3H5D2N3O2
Molecular Weight	120.12 g/mol
Synonyms	Guanidinoacetic-d2 Acid; N-Amidino-d2-glycine; (Amino-d2)(iminomethyl)aminoacetic Acid; Glycocyamine-d2; 2-[(Amino-d2)(imino)methyl]aminoacetic Acid; N-Guanylglycine-d2; Deutero-Guanidinoacetic Acid; GAA-d2
EINECS	Contact for details

Quality Control

Our Guanidineacetic--D2 Acid is manufactured under strict quality systems to ensure high isotopic and chemical purity suitable for analytical and research applications. Each batch is characterized by advanced spectroscopic and chromatographic methods, including NMR, MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (D-enrichment), chemical purity, and analytical data is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.