Description

Methyl (6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetate hydrochloride is a high-purity, synthetically derived chemical building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Organic Synthesis Building Block: Used in the construction of complex tetrahydroisoquinoline-based alkaloids and other heterocyclic compounds.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating enzyme inhibition and receptor-ligand interactions.

Basic Information

Product Name	Methyl (6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetate Hydrochloride
CAS No.	1172366-78-7
Molecular Formula	C₁₄H₂₀ClNO₄
Molecular Weight	301.77 g/mol
Synonyms	Methyl 2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetate hydrochloride; 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-isoquinolineacetic acid methyl ester hydrochloride; Methyl (6,7-dimethoxy-1,2,3,4-tetrahydro-1-isoquinolyl)acetate hydrochloride; Methyl 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-1-yl)acetate hydrochloride; 1172366-78-7
EINECS	Contact for details

Quality Control

Our Methyl (6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetate hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.