Description

Diphenyl 1-Amino-2-Phenylethylphosphonate Hydrochloride is a high-purity, organophosphorus chemical building block with significant synthetic utility. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its phosphonate moiety for biological activity.
• Ligand Synthesis: Serves as a precursor for chiral phosphine-phosphite or aminophosphine ligands used in asymmetric catalysis.
• Peptidomimetics: Incorporated into peptide analogs to enhance stability and modulate biological activity.
• Chemical Biology Probes: Utilized in the creation of activity-based probes for studying enzyme function and mechanism.
• Material Science: A potential monomer or additive in the development of specialized polymers and coatings.

Basic Information

Product Name	Diphenyl 1-Amino-2-Phenylethylphosphonate Hydrochloride
CAS No.	1171995-49-5
Molecular Formula	C20H21NO3P·HCl
Molecular Weight	399.82 g/mol (Hydrochloride salt)
Synonyms	1-Amino-2-phenylethylphosphonic Acid Diphenyl Ester Hydrochloride; (1-Amino-2-phenylethyl)phosphonic Acid Diphenyl Ester Hydrochloride; Diphenyl (1-Amino-2-phenylethyl)phosphonate HCl; α-Aminobenzylphosphonic Acid Diphenyl Ester Hydrochloride; Phosphonic acid, P-(1-amino-2-phenylethyl)-, diphenyl ester, hydrochloride; (R/S)-Diphenyl 1-amino-2-phenylethylphosphonate hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Diphenyl 1-Amino-2-Phenylethylphosphonate Hydrochloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay, chiral purity (if applicable), and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.