Description

5-(Trifluoromethyl)-7-Azaindole-3-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative featuring a trifluoromethyl group, a key structural motif in modern medicinal chemistry. This compound serves as a versatile and valuable pharmaceutical intermediate for the synthesis of novel active ingredients. It is primarily required by research organizations and pharmaceutical companies engaged in drug discovery and development, particularly for targeting kinase and enzyme inhibition.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of small molecule drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and pharmacokinetic properties.
• Agrochemical Development: Serves as a precursor for creating novel active ingredients in crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Material Science: Potential precursor for advanced organic materials and ligands in catalysis.

Basic Information

Product Name	5-(Trifluoromethyl)-7-Azaindole-3-Carboxylic Acid
CAS No.	1171920-15-2
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 5-Trifluoromethyl-7-azaindole-3-carboxylic acid; 5-CF3-7-Azaindole-3-carboxylic acid; 5-(Trifluoromethyl)-7-aza-1H-indole-3-carboxylic acid; 5-(Trifluoromethyl)-7-azaindole-3-carboxylate
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-7-Azaindole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.