Description

Methyl 1,2,3,4-Tetrahydroisoquinoline-4-Carboxylate Hcl is a high-purity organic salt serving as a critical building block in advanced chemical synthesis. This compound is valued for its role as a versatile intermediate in the development of complex molecules with targeted biological activity. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) in academic and industrial R&D labs.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct tetrahydroisoquinoline-based frameworks, which are common motifs in natural products and bioactive molecules.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides.

Basic Information

Product Name	Methyl 1,2,3,4-Tetrahydroisoquinoline-4-Carboxylate Hydrochloride
CAS No.	1171535-51-5
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	Methyl 1,2,3,4-tetrahydro-4-isoquinolinecarboxylate hydrochloride; 1,2,3,4-Tetrahydroisoquinoline-4-carboxylic acid methyl ester hydrochloride; Methyl 4-carboxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 4-(Methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; THIQ-4-COOMe HCl; 4-Carbomethoxy-1,2,3,4-tetrahydroisoquinoline HCl
EINECS	Contact for details

Quality Control

Our Methyl 1,2,3,4-Tetrahydroisoquinoline-4-Carboxylate Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.