Description

Ethyl 2-[(Chloroacetyl)Amino]-5,5,7,7-Tetramethyl-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-3-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• API Synthesis: Serves as a key building block for constructing complex molecules targeting specific biological pathways.
• Organic Synthesis Research: Used in academic and industrial R&D for developing new synthetic methodologies involving fused thienopyridine systems.
• Preclinical Development: Supplied for the production of compounds used in pharmacological screening and early-stage toxicity studies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule fabrication.
• Chemical Reference Standard: Can be utilized as a high-purity standard for analytical method development and validation.

Basic Information

Product Name	Ethyl 2-[(Chloroacetyl)Amino]-5,5,7,7-Tetramethyl-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-3-Carboxylate Hydrochloride
CAS No.	1171150-66-5
Molecular Formula	C19H28ClN2O3S • HCl
Molecular Weight	437.86 g/mol (Free base: 401.95 g/mol)
Synonyms	Ethyl 2-[(2-chloroacetamido)]-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate hydrochloride; 2-[(Chloroacetyl)amino]-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid ethyl ester hydrochloride; Thieno[2,3-c]pyridine-3-carboxylate derivative; CAS 1171150-66-5
EINECS	Contact for details

Quality Control

Our Ethyl 2-[(Chloroacetyl)Amino]-5,5,7,7-Tetramethyl-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-3-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.