Description

3-(1H-Indol-2-Yl)-2-Methyl-1-Oxo-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid CAS NO 1170819-00-7 is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• API Development: Employed in the research and development stages for creating new Active Pharmaceutical Ingredients (APIs) with tetrahydroisoquinoline and indole scaffolds.
• Biochemical Reagent: Acts as a specialized reagent or reference standard in biochemical assays and pharmacological testing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-(1H-Indol-2-Yl)-2-Methyl-1-Oxo-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid
CAS No.	1170819-00-7
Molecular Formula	C20H16N2O3
Molecular Weight	332.36 g/mol
Synonyms	3-(1H-Indol-2-yl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid; 2-Methyl-3-(1H-indol-2-yl)-1-oxo-1,2,3,4-tetrahydro-4-isoquinolinecarboxylic acid; 4-Carboxy-2-methyl-3-(1H-indol-2-yl)-1,2,3,4-tetrahydroisoquinolin-1-one; 1170819-00-7; Tetrahydroisoquinoline-4-carboxylic acid derivative; Indole-tetrahydroisoquinoline conjugate
EINECS	Contact for details

Quality Control

Our production of 3-(1H-Indol-2-Yl)-2-Methyl-1-Oxo-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with research-grade specifications. Our commitment to consistent purity and reliable supply supports critical R&D timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and kept in a low-humidity environment. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.