Description

1-Chloro-7-Iodoisoquinoline is a high-value halogenated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional halogen pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its reactive halogen sites for further functionalization.
• Material Science: Building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced organic electronic materials.
• Cross-Coupling Reactions: Excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions, leveraging the iodine moiety for carbon-carbon bond formation.
• Nucleophilic Substitution: The chlorine atom provides a site for nucleophilic aromatic substitution, enabling the introduction of amines, alkoxides, and other nucleophiles.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	1-Chloro-7-Iodoisoquinoline
CAS No.	1170704-54-7
Molecular Formula	C9H5ClIN
Molecular Weight	289.50 g/mol
Synonyms	7-Iodo-1-chloroisoquinoline; Isoquinoline, 1-chloro-7-iodo-; 1-Chloro-7-iodo-isoquinoline; 1170704-54-7; 1-Chloro-7-iodoisoquinoline; 1-Cl-7-I-isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloro-7-Iodoisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture uptake. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.