Description

4-Amino-6-Bromo-3,4-Dihydro-2H-1-Benzothiopyran Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1170470-60-6. This compound is a critical building block in modern organic synthesis, valued for its unique benzothiopyran scaffold and functionalized amine and bromo groups. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and complex chemical libraries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Organic Synthesis Building Block: Used in complex multi-step syntheses, including cross-coupling reactions, due to the reactive bromine substituent.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the generation of focused compound libraries for high-throughput screening.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	4-Amino-6-Bromo-3,4-Dihydro-2H-1-Benzothiopyran Hydrochloride
CAS No.	1170470-60-6
Molecular Formula	C9H11BrClNS
Molecular Weight	280.61 g/mol
Synonyms	6-Bromo-3,4-dihydro-2H-1-benzothiopyran-4-amine hydrochloride; 4-Amino-6-bromo-3,4-dihydro-2H-1-benzothiopyran HCl; 4-Amino-6-bromochroman-4-thiol hydrochloride (tautomeric form); 1170470-60-6; 4-Amino-6-bromo-3,4-dihydro-2H-thiochromene hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Bromo-3,4-Dihydro-2H-1-Benzothiopyran Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.