Description

4-[1-(3,4-Dichlorophenyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]-1,3-Thiazol-2-Amine Hydrochloride is a high-purity organic intermediate of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, particularly for neurological and psychiatric applications.
• Research Chemical: Used in academic and industrial research settings to study structure-activity relationships (SAR) and biological pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex target molecules for pre-clinical and clinical trials.
• Chemical Biology Probe: Utilized to investigate protein-ligand interactions and enzyme inhibition mechanisms in biochemical assays.
• Process Chemistry Development: Serves as a standard or reference material for scaling up and optimizing synthetic routes in pilot plants.

Basic Information

Product Name	4-[1-(3,4-Dichlorophenyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]-1,3-Thiazol-2-Amine Hydrochloride
CAS No.	1170210-77-1
Molecular Formula	C15H14Cl3N3S
Molecular Weight	378.71 g/mol
Synonyms	4-[1-(3,4-Dichlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-1,3-thiazol-2-amine hydrochloride; 2-Amino-4-[1-(3,4-dichlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]thiazole hydrochloride; 1170210-77-1; 4-(1-(3,4-Dichlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)thiazol-2-amine HCl; Thiazol-2-amine, 4-[1-(3,4-dichlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 4-[1-(1-(3,4-Dichlorophenyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]-1,3-Thiazol-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.