Description

Carbamic Acid, n-[(1S)-1-(Hydroxymethyl)-2-[1-[(4-Methylphenyl)Sulfonyl]-1H-Imidazol-4-Yl]Ethyl]-, 1,1-Dimethylethyl Ester is a sophisticated chiral building block and protected intermediate of significant interest in advanced organic synthesis. This compound is critical for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and fine chemicals, where precise stereochemistry and functional group protection are paramount. Its primary value lies in enabling the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, by serving as a key precursor.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new drug candidates, particularly in protease inhibitor and other targeted therapeutic classes.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and mimetics for biochemical research and drug discovery programs.
• Agrochemical Research: Serves as a building block for developing novel, high-efficacy crop protection agents with specific stereochemical requirements.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified compounds for studying enzyme mechanisms and biological pathways.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of complex organic molecules.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	Carbamic Acid, n-[(1S)-1-(Hydroxymethyl)-2-[1-[(4-Methylphenyl)Sulfonyl]-1H-Imidazol-4-Yl]Ethyl]-, 1,1-Dimethylethyl Ester
CAS No.	1169760-85-3
Molecular Formula	C19H27N3O5S
Molecular Weight	409.50 g/mol
Synonyms	tert-Butyl N-[(1S)-1-(hydroxymethyl)-2-[1-[(4-methylphenyl)sulfonyl]imidazol-4-yl]ethyl]carbamate; (S)-tert-Butyl (1-(hydroxymethyl)-2-(1-tosyl-1H-imidazol-4-yl)ethyl)carbamate; (S)-N-Boc-2-(1-tosyl-1H-imidazol-4-yl)ethanolamine; Boc-Protected Tryptamine Derivative; 1,1-Dimethylethyl N-[(1S)-1-(hydroxymethyl)-2-[1-[(4-methylphenyl)sulfonyl]-1H-imidazol-4-yl]ethyl]carbamate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical research and development. Each lot is subjected to comprehensive analytical characterization, including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment. We operate under a quality management system and can support development toward cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to maintain stability. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.