Description

Phosphonoethanolamine-D4 is a high-purity, deuterium-labeled analog of phosphonoethanolamine, a key intermediate in phospholipid metabolism. This stable isotope-labeled compound is essential for advanced research and development requiring precise analytical tracking and quantification. It is primarily utilized by scientists and manufacturers in the fields of pharmaceutical development, metabolic research, and analytical chemistry for applications such as internal standards in mass spectrometry.

Application

• Internal Standard for Mass Spectrometry (LC-MS/MS, GC-MS): Provides accurate quantification of endogenous phosphonoethanolamine and related metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Used in deuterium-labeling studies to investigate phospholipid biosynthesis and turnover in cell culture and animal models.
• Pharmaceutical R&D: Supports the development and validation of bioanalytical methods for drug candidates targeting metabolic disorders.
• Biochemical Research: Serves as a critical reagent in enzymatic assays and studies of aminophosphonate biochemistry.
• Diagnostic Assay Development: Employed in the creation of high-sensitivity clinical tests for metabolic conditions.

Basic Information

Product Name	Phosphonoethanolamine-D4
CAS No.	1169692-38-9
Molecular Formula	C₂H₃D₄NO₃P
Molecular Weight	144.10 g/mol (deuterated form)
Synonyms	2-Aminoethylphosphonic Acid-d4; Aminoethylphosphonate-d4; AEP-d4; Deuterated Phosphonoethanolamine; (2-Aminoethyl)phosphonic Acid-d4; Ethanolamine-1,1,2,2-d4 Phosphonate; NSC 266798-d4
EINECS	Contact for details

Quality Control

Our Phosphonoethanolamine-D4 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is accompanied by comprehensive analytical documentation, including NMR (¹H, ²H, ³¹P) and Mass Spectrometry data to confirm deuteration level and chemical identity. Certificates of Analysis (COA) detailing purity, isotopic enrichment, and solvent content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.