Description

(E)-Methyl 1-Acetyl-3-(Methoxy(Phenyl)Methylene)-2-Oxoindoline-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the oxindole class of compounds. This compound matters as a critical building block in the synthesis of complex molecules, offering a defined stereochemistry and functional group array essential for modern drug discovery. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in developing novel therapeutic agents, particularly in oncology and neurological disease research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of biologically active oxindole derivatives and kinase inhibitors.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex heterocyclic frameworks.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in API manufacturing.
• Academic Research: Applied in university and institutional labs for studying novel organic reactions and catalysis.

Basic Information

Product Name	(E)-Methyl 1-Acetyl-3-(Methoxy(Phenyl)Methylene)-2-Oxoindoline-6-Carboxylate
CAS No.	1168152-07-5
Molecular Formula	C20H17NO5
Molecular Weight	351.35 g/mol
Synonyms	Methyl 1-acetyl-3-[(E)-methoxy(phenyl)methylene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate; (E)-1-Acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylic acid methyl ester; 6-Methoxycarbonyl-1-acetyl-3-(methoxy(phenyl)methylene)oxindole; (E)-Isomer of Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate; 1H-Indole-6-carboxylic acid, 1-acetyl-2,3-dihydro-3-[(E)-methoxy(phenyl)methylene]-2-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Our (E)-Methyl 1-Acetyl-3-(Methoxy(Phenyl)Methylene)-2-Oxoindoline-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.