Description

(E)-1-[2-(4-Chlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]-3-(4-Methoxyphenyl)-2-Propen-1-One is a high-purity, synthetic organic compound featuring a chalcone core integrated with a substituted thiazole moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile key building block for medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting inflammation, cancer, or infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as an intermediate for creating novel pesticides or herbicides, leveraging the bioactivity of the thiazole and chalcone structures.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemicals.
• Chemical Biology Probe: Utilized in academic and industrial research to study biological pathways and protein interactions.
• Material Science Research: Investigated as a potential monomer or component for developing organic electronic materials due to its conjugated system.

Basic Information

Product Name	(E)-1-[2-(4-Chlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]-3-(4-Methoxyphenyl)-2-Propen-1-One
CAS No.	1164520-79-9
Molecular Formula	C20H16ClNO2S
Molecular Weight	369.86 g/mol
Synonyms	(E)-1-[2-(4-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-3-(4-methoxyphenyl)prop-2-en-1-one; 2-Propen-1-one, 1-[2-(4-chlorophenyl)-4-methyl-5-thiazolyl]-3-(4-methoxyphenyl)-, (E)-; 4'-Methoxy-4-chlorochalcone thiazole derivative; Chalcone-thiazole hybrid; 5-(3-(4-Methoxyphenyl)acryloyl)-2-(4-chlorophenyl)-4-methylthiazole; (E)-3-(4-Methoxyphenyl)-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]prop-2-en-1-one
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our production of this advanced intermediate adheres to current Good Manufacturing Practice (GMP) principles where applicable. Every batch is thoroughly characterized and tested. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.