Description

(E)-3-(4-Chlorophenyl)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-2-Propen-1-One is a high-purity, synthetic organic compound belonging to the chalcone-thiazole hybrid class, valued for its role as a versatile chemical intermediate. Its molecular architecture makes it a critical building block for advanced research and development in medicinal chemistry and material science. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for synthesizing novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting inflammation, cancer, and infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents with optimized efficacy.
• Chemical Biology Probe: Employed in biochemical assays to study protein interactions and enzyme inhibition mechanisms.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to create complex heterocyclic compounds and functional materials.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents and pesticides.
• Material Science Applications: Explored for the development of organic semiconductors and photoactive materials due to its conjugated system.

Basic Information

Product Name	(E)-3-(4-Chlorophenyl)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-2-Propen-1-One
CAS No.	1164520-66-4
Molecular Formula	C19H14ClNOS
Molecular Weight	339.84 g/mol
Synonyms	(E)-1-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)-3-(4-chlorophenyl)prop-2-en-1-one; 3-(4-Chlorophenyl)-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-propen-1-one; 2-Propen-1-one, 3-(4-chlorophenyl)-1-(4-methyl-2-phenyl-5-thiazolyl)-, (E)-; Chalcone-thiazole derivative; 5-(3-(4-Chlorophenyl)acryloyl)-4-methyl-2-phenylthiazole
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Chlorophenyl)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.