Description

(E)-n-(3-Cyano-4,5,6,7-Tetrahydrobenzo[B]Thiophen-2-Yl)-3-(Furan-2-Yl)Acrylamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining tetrahydrobenzothiophene and furan moieties. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted small-molecule drugs.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: A potential building block for compounds targeting specific protein kinases involved in cancer and inflammatory diseases.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein function.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Used in university laboratories for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	(E)-n-(3-Cyano-4,5,6,7-Tetrahydrobenzo[B]Thiophen-2-Yl)-3-(Furan-2-Yl)Acrylamide
CAS No.	1164519-78-1
Molecular Formula	C₁₆H₁₂N₂O₂S
Molecular Weight	296.35 g/mol
Synonyms	(E)-N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-3-(2-furyl)acrylamide; 2-Propenamide, N-(3-cyano-4,5,6,7-tetrahydro-2-benzothienyl)-3-(2-furanyl)-, (2E)-; (E)-N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-3-(furan-2-yl)prop-2-enamide; 1164519-78-1; (2E)-N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-3-(furan-2-yl)prop-2-enamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), suitable for research and development applications. Each batch is accompanied by comprehensive analytical data, including HPLC chromatograms and NMR spectra. Certificates of Analysis (COA) are available upon request, detailing identity, purity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants and storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.