Description

Ethyl 4-(Dimethylamino)-3-([(Dimethylamino)Methylene]Amino)Thieno[2,3-B]Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and antiviral research domains.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• API Synthesis: A key building block for constructing the core scaffold of target APIs, especially in kinase inhibitor programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 4-(Dimethylamino)-3-([(Dimethylamino)Methylene]Amino)Thieno[2,3-B]Pyridine-2-Carboxylate
CAS No.	1164506-81-3
Molecular Formula	C15H20N4O2S
Molecular Weight	320.41 g/mol
Synonyms	Ethyl 4-(dimethylamino)-3-[(dimethylamino)methylideneamino]thieno[2,3-b]pyridine-2-carboxylate; 2-Thiophenecarboxylic acid, 4-(dimethylamino)-3-[[(dimethylamino)methylene]amino]thieno[2,3-b]pyridine-2-, ethyl ester; 1164506-81-3; Thieno[2,3-b]pyridine-2-carboxylate derivative; DMAP-thienopyridine intermediate
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-(Dimethylamino)-3-([(Dimethylamino)Methylene]Amino)Thieno[2,3-B]Pyridine-2-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting cGMP-compliant development and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.