Description

Ethyl 2-Amino-5-(2,2,2-Trifluoroethyl)Thiophene-3-Carboxylate is a high-value, multi-functional heterocyclic building block featuring a thiophene core substituted with an amino group and a trifluoroethyl moiety. This compound is specifically engineered to serve as a critical intermediate in advanced organic synthesis, offering unique reactivity and physicochemical properties derived from its fluorine-containing side chain. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoroethyl group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized polymers and organic electronic materials, leveraging the thiophene unit's conductive properties.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic research applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	Ethyl 2-Amino-5-(2,2,2-Trifluoroethyl)Thiophene-3-Carboxylate
CAS No.	1160720-50-2
Molecular Formula	C9H10F3NO2S
Molecular Weight	253.24 g/mol
Synonyms	2-Amino-5-(2,2,2-trifluoroethyl)thiophene-3-carboxylic acid ethyl ester; Ethyl 2-amino-5-(2,2,2-trifluoroethyl)-3-thiophenecarboxylate; 5-(2,2,2-Trifluoroethyl)-2-aminothiophene-3-carboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-(2,2,2-trifluoroethyl)-, ethyl ester; 1160720-50-2; ATEC; Trifluoroethyl Thiophene Ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-Amino-5-(2,2,2-Trifluoroethyl)Thiophene-3-Carboxylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.