Description

p-[(1R,2R)-1,2-Dihydroxypropyl]-Phosphonic Acid Ammonium Salt is a high-purity, stereochemically defined organophosphorus compound that serves as a critical intermediate and functional additive. Its value lies in its unique combination of a chiral dihydroxypropyl moiety with a phosphonic acid group, offering chelating and metal-binding properties for advanced applications. This material is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop novel active ingredients or sophisticated metal-complexing agents.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly those targeting bone metabolism or requiring specific metal chelation.
• Agrochemical Synthesis: Precursor for developing advanced herbicides, plant growth regulators, or fungicides with enhanced activity and environmental profile.
• Metal Sequestrant & Chelating Agent: Used in water treatment formulations, industrial cleaning solutions, and as a stabilizer in polymer production to control metal ion catalysis.
• Catalyst Ligand: Serves as a ligand for asymmetric catalysis in fine chemical synthesis, leveraging its chiral centers for enantioselective reactions.
• Biomimetic Mineralization Studies: Research tool in material science for studying calcium phosphate crystallization, relevant to bone graft materials and dental applications.
• Analytical Reagent: Used in analytical chemistry as a standard or reagent for method development involving phosphonate analysis or chiral separation.

Basic Information

Item	Details
Product Name	p-[(1R,2R)-1,2-Dihydroxypropyl]-Phosphonic Acid Ammonium Salt
CAS No.	1160525-87-0
Molecular Formula	C₃H₁₃NO₆P
Molecular Weight	190.11 g/mol
Synonyms	(1R,2R)-1,2-Dihydroxypropylphosphonic Acid Ammonium Salt; Ammonium (1R,2R)-1,2-dihydroxypropylphosphonate; (R,R)-1,2-Dihydroxypropylphosphonic Acid Ammonium Salt; p-(1,2-Dihydroxypropyl)-Phosphonic Acid Ammonium Salt (stereospecific); AMPA analogue (chiral); Chiral Hydroxypropylphosphonate Ammonium Salt
EINECS	Contact for details

Quality Control

Every batch of p-[(1R,2R)-1,2-Dihydroxypropyl]-Phosphonic Acid Ammonium Salt is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure identity, purity, and stereochemical integrity for your critical applications. Certificates of Analysis (COA) detailing assay, chiral purity, and impurity profiles are available upon request and align with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent absorption of water and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.