Description

8-Chloro-2-(4-Ethylphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical building block designed for advanced synthesis. This compound matters as a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research, offering a versatile quinoline core with reactive acyl chloride and chloro functionalities. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with quinoline-based structures.
• Material Science Research: Serves as a precursor for creating organic ligands, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent probes and molecular tags for biological imaging and diagnostics.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	8-Chloro-2-(4-Ethylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160256-02-9
Molecular Formula	C19H13Cl2NO
Molecular Weight	342.22 g/mol
Synonyms	8-Chloro-2-(4-ethylphenyl)quinoline-4-carbonyl chloride; 2-(4-Ethylphenyl)-8-chloroquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-[4-ethylphenyl]-; 1160256-02-9; 8-Chloro-2-(p-ethylphenyl)-4-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(4-Ethylphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.