Description

4-Cyano-Isoindoline Hcl is a high-purity chemical intermediate of significant importance in modern pharmaceutical research and development. This compound serves as a critical building block for the synthesis of complex molecules, enabling the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for projects targeting neurological and oncological pathways. Its defined structure and purity are essential for ensuring reproducible results in sensitive synthetic processes.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, especially those with isoindoline or related heterocyclic cores.
• Organic Synthesis Building Block: Used in research laboratories for constructing complex organic molecules, leveraging the reactivity of the cyano group and the secondary amine after deprotection.
• Medicinal Chemistry Research: Employed in the design and development of new chemical entities for screening against various biological targets.
• Precursor for Functional Materials: Can serve as a starting material in the development of specialized organic compounds for material science applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations that require reliable, high-quality intermediates for client projects.

Basic Information

Product Name	4-Cyano-Isoindoline Hcl
CAS No.	1159825-57-6
Molecular Formula	C9H9ClN2
Molecular Weight	180.63 g/mol
Synonyms	4-Cyano-2,3-dihydro-1H-isoindole hydrochloride; Isoindoline-4-carbonitrile hydrochloride; 1H-Isoindole-4-carbonitrile, 2,3-dihydro-, hydrochloride (1:1); 4-CN-Isoindoline HCl; 4-Cyanoisoindoline hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Cyano-Isoindoline Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We are committed to meeting the stringent requirements of research and development applications, and specifications can be aligned with client needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.