Description

2-Boc-Octahydropyrazino[1,2-A]Pyrazine is a protected heterocyclic amine derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its role as a versatile intermediate for constructing complex nitrogen-containing scaffolds, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in drug discovery, especially for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Peptidomimetic Chemistry: Used to introduce constrained, bicyclic diamine structures that mimic peptide backbones, enhancing metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe Synthesis: Employed in the construction of molecular probes for studying enzyme function and biological pathways.
• Academic and Contract Research: A valuable reagent for research institutions and CROs (Contract Research Organizations) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Boc-Octahydropyrazino[1,2-A]Pyrazine
CAS No.	1159825-34-9
Molecular Formula	C13H23N3O2
Molecular Weight	253.34 g/mol
Synonyms	2-(tert-Butoxycarbonyl)octahydropyrazino[1,2-a]pyrazine; 1,2,3,4,6,7,8,8a-Octahydropyrazino[1,2-a]pyrazine-2-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl octahydropyrazino[1,2-a]pyrazine-2(1H)-carboxylate; 2-Boc-octahydropyrazino[1,2-a]pyrazine; BOPP-Boc; Boc-Protected Octahydropyrazinopyrazine.
EINECS	Contact for details

Quality Control

Our 2-Boc-Octahydropyrazino[1,2-A]Pyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure it meets the stringent requirements for pharmaceutical R&D and other advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.