Description

5-Bromothiophen-3-Amine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial importance. Its core value lies in its functionalized thiophene and amine groups, which are critical for constructing complex molecules in medicinal chemistry and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for synthesis and development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the bromothiophene scaffold.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and solar cells.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical reactions, catalytic processes, and the development of novel heterocyclic compounds.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal catalysis and coordination chemistry due to the presence of the amine functionality.
• Dye and Pigment Industry: Acts as an intermediate in the manufacture of specialized dyes and functional pigments.

Basic Information

Product Name	5-Bromothiophen-3-Amine Hydrochloride
CAS No.	1159823-91-2
Molecular Formula	C4H5BrClNS
Molecular Weight	222.51 g/mol
Synonyms	3-Amino-5-bromothiophene hydrochloride; 5-Bromo-3-thiophenamine hydrochloride; 5-Bromothiophen-3-ylamine hydrochloride; 3-Thiophenamine, 5-bromo-, hydrochloride (1:1); 5-Bromo-3-aminothiophene HCl
EINECS	Contact for details

Quality Control

Our 5-Bromothiophen-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.