Description

1,2,3,4-Tetrahydro-4-Isoquinolinamine Dihydrochloride is a high-purity, pharmaceutically relevant organic salt, identified by CAS NO 1159822-32-8. This compound serves as a critical building block (API intermediate) in the synthesis of complex molecules, offering researchers and manufacturers a reliable starting material with defined stereochemistry. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting neurological and cardiovascular disorders.
• Organic Synthesis Building Block: Used in the construction of complex isoquinoline-based heterocycles for medicinal chemistry research.
• Chemical Research & Development: Serves as a standard or reagent in method development and structure-activity relationship (SAR) studies.
• Academic Research: Utilized in university and institutional labs for studying synthetic pathways and novel compound libraries.
• Process Chemistry: Employed in scale-up and optimization studies for the production of active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	1,2,3,4-Tetrahydro-4-Isoquinolinamine Dihydrochloride
CAS No.	1159822-32-8
Molecular Formula	C9H14Cl2N2
Molecular Weight	221.13 g/mol
Synonyms	4-Amino-1,2,3,4-tetrahydroisoquinoline dihydrochloride; 1,2,3,4-Tetrahydroisoquinolin-4-amine dihydrochloride; 4-Isoquinolinamine, 1,2,3,4-tetrahydro-, dihydrochloride; THIQ-4-amine dihydrochloride; 4-Aminotetrahydroisoquinoline dihydrochloride; 1,2,3,4-Tetrahydro-4-isoquinolinamine hydrochloride (1:2); 4-ATIQ dihydrochloride
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-4-Isoquinolinamine Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.