Description

[3-(4-Fluorophenyl)-Isoxazol-4-Yl]-Methanol is a high-value fluorinated isoxazole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a fluorinated aromatic ring with a reactive hydroxymethyl group on the isoxazole heterocycle, enabling precise modifications for creating novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorophenyl-isoxazole moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and organic semiconductors, due to its rigid, conjugated structure.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke fluorinated compounds for client projects.

Basic Information

Product Name	[3-(4-Fluorophenyl)-Isoxazol-4-Yl]-Methanol
CAS No.	1159252-41-1
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	4-(Hydroxymethyl)-3-(4-fluorophenyl)isoxazole; (3-(4-Fluorophenyl)isoxazol-4-yl)methanol; 3-(4-Fluorophenyl)-4-(hydroxymethyl)-1,2-oxazole; 4-Fluorophenyl-isoxazole methanol derivative; Isoxazole-4-methanol, 3-(4-fluorophenyl)-; 1159252-41-1; 4-Fluorophenyl isoxazolyl methanol
EINECS	Contact for details

Quality Control

Our [3-(4-Fluorophenyl)-Isoxazol-4-Yl]-Methanol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.