Description

[7-(Trimethylammonium)Hepyl] Methanethiosulfonate Bromide is a specialized, high-purity chemical reagent designed for advanced bioconjugation and protein chemistry applications. Its core value lies in its ability to serve as a site-specific, thiol-reactive labeling and crosslinking agent, enabling precise modification of biomolecules. This compound is essential for researchers and manufacturers in the fields of biopharmaceutical development, proteomics, and diagnostic assay production who require reliable and consistent reagents for their critical workflows.

Application

• Site-Specific Protein Labeling: Covalent attachment of fluorophores, biotin, or other probes to cysteine residues in proteins and antibodies for imaging, detection, and diagnostic applications.
• Bioconjugation for ADC Development: Used in the synthesis and research of Antibody-Drug Conjugates (ADCs) to link cytotoxic payloads to antibodies via engineered cysteine residues.
• Surface Immobilization Chemistry: Functionalization of gold surfaces, nanoparticles, or biosensor chips with biomolecules for analytical and diagnostic devices.
• Structural Biology Studies: Introduction of spin labels or other probes for techniques like Electron Paramagnetic Resonance (EPR) spectroscopy to study protein structure and dynamics.
• Crosslinking Agent: For studying protein-protein interactions or creating stable protein complexes through disulfide bridge formation.
• Peptide Modification: Selective modification of synthetic peptides containing cysteine to introduce functional handles or tags.

Basic Information

Product Name	[7-(Trimethylammonium)Hepyl] Methanethiosulfonate Bromide
CAS No.	1159174-26-1
Molecular Formula	C11H24BrNO2S2
Molecular Weight	346.35 g/mol
Synonyms	MTSL reagent analog; (7-(Trimethylammonio)heptyl) methanethiosulfonate bromide; MTSEA-heptyl-TMA; Thiol-reactive bioconjugation reagent; Trimethylammonium heptyl MTS; Protein labeling reagent; Cysteine-specific modification reagent; S-(7-Trimethylammoniumheptyl) methanethiosulfonate bromide
EINECS	Contact for details

Quality Control

Every batch of [7-(Trimethylammonium)Hepyl] Methanethiosulfonate Bromide is manufactured and tested under stringent quality management systems to ensure the high purity and consistency required for sensitive life science research. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.