Description

4-(5-Amino-1 H-Benzoimidazol-2-Yl)-Benzoic Acid Dihydrochloride is a high-purity, functionalized benzimidazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel small molecule therapeutics and research chemicals. It is primarily utilized by pharmaceutical R&D, biotechnology, and fine chemical synthesis sectors for creating targeted molecular libraries and investigating new biological pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting various enzyme families and receptors.
• Biochemical Research: Used as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds due to its reactive amino and carboxylic acid functional groups.
• Agrochemical Development: Potential intermediate for creating new active ingredients in crop protection products.
• Material Science Research: Investigated for the development of organic semiconductors or advanced polymeric materials with specific electronic properties.

Basic Information

Item	Detail
Product Name	4-(5-Amino-1 H-Benzoimidazol-2-Yl)-Benzoic Acid Dihydrochloride
CAS No.	1158534-13-4
Molecular Formula	C14H12N3O2 · 2HCl
Molecular Weight	339.18 g/mol (Free base: 254.27 g/mol)
Synonyms	4-(5-Amino-1H-benzo[d]imidazol-2-yl)benzoic acid dihydrochloride; 2-(4-Carboxyphenyl)-5-amino-1H-benzimidazole dihydrochloride; 5-Amino-2-(4-carboxyphenyl)-1H-benzimidazole dihydrochloride; Benzoic acid, 4-(5-amino-1H-benzimidazol-2-yl)-, dihydrochloride; CAS 1158534-13-4
EINECS	Contact for details

Quality Control

Our production of 4-(5-Amino-1 H-Benzoimidazol-2-Yl)-Benzoic Acid Dihydrochloride adheres to stringent internal quality standards, ensuring batch-to-batch consistency and reliability for research and development purposes. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to GMP-compliant practices where required, and specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.