Description

2-(3-Hydroxy-Propyl)-1 H-Benzoimidazole-5-Carboxylic Acid Hydrochloride is a high-purity organic salt of significant interest in advanced pharmaceutical synthesis and fine chemical research. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting complex biological pathways. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and specialty chemical industries for creating new molecular entities with enhanced therapeutic profiles.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel benzimidazole-derived active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a scaffold or reagent in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Protease Inhibitor Development: Potential building block for the synthesis of molecules designed to inhibit specific enzymes like proteases.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalytic systems or diagnostic assays.
• Fine Chemical Synthesis: Serves as a versatile intermediate for creating specialty chemicals with specific functional properties.

Basic Information

Product Name	2-(3-Hydroxy-Propyl)-1 H-Benzoimidazole-5-Carboxylic Acid Hydrochloride
CAS No.	1158454-40-0
Molecular Formula	C11H13N2O3·HCl
Molecular Weight	256.69 g/mol
Synonyms	2-(3-Hydroxypropyl)-1H-benzimidazole-5-carboxylic acid hydrochloride; 1H-Benzimidazole-5-carboxylic acid, 2-(3-hydroxypropyl)-, hydrochloride; 2-(3-Hydroxypropyl)-1H-benzo[d]imidazole-5-carboxylic acid HCl; Benzimidazole-5-carboxylic acid derivative, 2-(3-hydroxypropyl)- hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(3-Hydroxy-Propyl)-1 H-Benzoimidazole-5-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.