Description

Methyl 7-Fluoro-1H-Indole-2-Carboxylate is a high-purity fluorinated indole derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on novel active ingredients, especially those targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in serotonin receptor modulators and kinase inhibitors.
• Agrochemical Research: Used in the synthesis of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Serves as a starting material for creating specialized fluorinated organic compounds used in electronic materials and liquid crystals.
• Academic & R&D: A valuable reagent for methodological studies in fluorination chemistry and heterocyclic compound synthesis.
• Contract Manufacturing (CMO): Supplied to CMOs for the scale-up and production of client-specific target molecules under cGMP conditions where required.

Basic Information

Item	Detail
Product Name	Methyl 7-Fluoro-1H-Indole-2-Carboxylate
CAS No.	1158331-26-0
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	7-Fluoro-1H-indole-2-carboxylic acid methyl ester; Methyl 7-fluoroindole-2-carboxylate; 2-Methoxycarbonyl-7-fluoroindole; 7-Fluoroindole-2-carboxylic acid methyl ester; 1H-Indole-2-carboxylic acid, 7-fluoro-, methyl ester; Methyl 7-fluoro-1H-indole-2-carboxylate; 1158331-26-0
EINECS	Contact for details

Quality Control

Our Methyl 7-Fluoro-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications from research to commercial-scale production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.