Description

1H-Indole, 7-Bromo-5-Fluoro-2,3-Dihydro- is a high-purity, halogenated indoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its unique molecular scaffold, which enables the construction of complex heterocyclic systems essential for pharmaceutical discovery and material science. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced activity profiles.
• Material Science: Serves as a precursor for organic electronic materials, including charge-transport layers and light-emitting components.
• Chemical Biology: Employed as a molecular probe or scaffold in the design of enzyme inhibitors and receptor ligands.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis and heterocyclic chemistry.
• Custom Synthesis: Starting material for the contract manufacturing of proprietary compounds and advanced intermediates.

Basic Information

Product Name	1H-Indole, 7-Bromo-5-Fluoro-2,3-Dihydro-
CAS No.	1156704-69-6
Molecular Formula	C8H7BrFN
Molecular Weight	216.05 g/mol
Synonyms	7-Bromo-5-fluoro-2,3-dihydro-1H-indole; 5-Fluoro-7-bromo-2,3-dihydroindole; 7-Bromo-5-fluoroindoline; 2,3-Dihydro-7-bromo-5-fluoro-1H-indole; 1H-Indole, 7-bromo-5-fluoro-2,3-dihydro-; 1156704-69-6; Br,5-F-Dihydroindole
EINECS	Contact for details

Quality Control

Our 1H-Indole, 7-Bromo-5-Fluoro-2,3-Dihydro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.