Description

5-Chloro-3-(Trifluoromethyl)-1-(4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde is a high-value, multi-functional pyrazole derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its molecular architecture, featuring chloro, trifluoromethyl, and fluorophenyl substituents, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Serves as a core scaffold for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl and halogen groups.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, aromatic structure and functional aldehyde group.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-Chloro-3-(Trifluoromethyl)-1-(4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde
CAS No.	1152960-75-2
Molecular Formula	C11H5ClF4N2O
Molecular Weight	292.62 g/mol
Synonyms	4-Pyrazolecarboxaldehyde, 5-chloro-1-(4-fluorophenyl)-3-(trifluoromethyl)-1H-; 1-(4-Fluorophenyl)-5-chloro-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde; 5-Chloro-1-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxaldehyde; 1152960-75-2; 5-Chloro-3-trifluoromethyl-1-(4-fluorophenyl)-1H-pyrazole-4-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-3-(Trifluoromethyl)-1-(4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.