Description

1H-Indole-2-Acetic Acid, 6-Fluoro-Alpha,α-Dimethyl-5-Nitro-, Phenylmethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex synthetic pathways. This compound matters for its role as a critical building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting specific receptor sites. Pharmaceutical R&D laboratories and fine chemical manufacturers need this ester for synthesizing potential drug candidates in areas such as oncology and neurology, where precise molecular modification is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development of new APIs, leveraging its indole and fluoronitro-substituted structure.
• Biochemical Research: Employed as a standard or reagent in studies investigating enzyme inhibition or receptor-ligand interactions.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for constructing complex heterocyclic compounds due to its reactive ester group and substituted indole core.
• Agrochemical Research: Potential intermediate in the development of new generation herbicides or plant growth regulators, exploring the biological activity of nitro- and fluoro-substituted indoles.

Basic Information

Item	Details
Product Name	1H-Indole-2-Acetic Acid, 6-Fluoro-Alpha,α-Dimethyl-5-Nitro-, Phenylmethyl Ester
CAS No.	1152311-77-7
Molecular Formula	C19H17FN2O4
Molecular Weight	356.35 g/mol
Synonyms	Benzyl 6-Fluoro-α,α-dimethyl-5-nitro-1H-indole-2-acetate; 6-Fluoro-α,α-dimethyl-5-nitro-1H-indole-2-acetic Acid Phenylmethyl Ester; 2-(6-Fluoro-α,α-dimethyl-5-nitro-1H-indol-2-yl)acetic Acid Benzyl Ester; (6-Fluoro-α,α-dimethyl-5-nitro-1H-indol-2-yl)acetic Acid Benzyl Ester; Benzyl (6-Fluoro-α,α-dimethyl-5-nitro-1H-indol-2-yl)acetate
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-2-Acetic Acid, 6-Fluoro-Alpha,α-Dimethyl-5-Nitro-, Phenylmethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); therefore, containers should be kept sealed under an inert atmosphere such as nitrogen or argon when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.