Description

1-Methyl-1H-Indazol-6-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, process development, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for constructing indazole-containing active pharmaceutical ingredients (APIs) and drug candidates in medicinal chemistry programs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for creating new carbon-carbon bonds, essential for synthesizing complex organic molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the indazole heterocycle.
• Material Science: A precursor for creating organic electronic materials, ligands for catalysis, and functional polymers.
• Chemical Biology: Employed in the synthesis of molecular probes and bioconjugates for studying biological systems.
• Contract Research & Manufacturing (CRO/CMO): A standard reagent for custom synthesis and scale-up projects requiring precise molecular assembly.

Basic Information

Product Name	1-Methyl-1H-Indazol-6-Boronic Acid
CAS No.	1150114-80-9
Molecular Formula	C8H9BN2O2
Molecular Weight	176.00 g/mol
Synonyms	1-Methyl-6-indazoleboronic acid; 1-Methyl-1H-indazole-6-boronic acid; 6-Borono-1-methyl-1H-indazole; (1-Methyl-1H-indazol-6-yl)boronic acid; B-(1-Methyl-1H-indazol-6-yl)boronic acid; 1-Methylindazole-6-boronic acid; 1-Methyl-1H-indazol-6-ylboronic acid
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Indazol-6-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.