Description

2-Amino-4-(Isopropoxycarbonyl)Phenylboronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its bifunctional structure, combining a reactive boronic acid group with a protected amino acid moiety, enabling precise cross-coupling and derivatization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, particularly for Suzuki-Miyaura coupling applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in creating novel herbicides and fungicides with targeted modes of action.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl structures central to many active compounds.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Peptide Mimetics & Conjugation: The isopropoxycarbonyl-protected amino group allows for the creation of peptide analogs and bioconjugates.
• Chemical Biology Probes: Useful for designing activity-based probes and sensors that target specific enzymes or biological pathways.

Basic Information

Item	Detail
Product Name	2-Amino-4-(Isopropoxycarbonyl)Phenylboronic Acid
CAS No.	1150114-64-9
Molecular Formula	C10H14BNO4
Molecular Weight	223.04 g/mol
Synonyms	2-Amino-4-(isopropoxycarbonyl)benzeneboronic acid; 4-(Isopropoxycarbonyl)-2-aminophenylboronic acid; 2-Amino-4-carboxyisopropyl ester phenylboronic acid; (2-Amino-4-(1-methylethoxycarbonyl)phenyl)boronic acid; B-[2-Amino-4-[(1-methylethoxy)carbonyl]phenyl]boronic acid; CAS 1150114-64-9; 2-Amino-4-isopropoxycarbonylphenylboronic Acid
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(Isopropoxycarbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions, such as in a glovebox or under an inert atmosphere, for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.