Description

2-Methyl-5-(Trifluoromethylsulfonyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative featuring a trifluoromethylsulfonyl (triflyl) substituent. This compound is a critical building block in modern synthetic chemistry, prized for its role in facilitating challenging cross-coupling reactions to create complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-couplings for constructing biaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the incorporation of the trifluoromethylsulfonyl group for enhanced bioactivity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as polymers for OLEDs or conductive films.
• Ligand and Catalyst Development: Employed to create novel boronate-based ligands for catalysis or as a handle for immobilizing catalysts on solid supports.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and sensors that leverage boronic acid chemistry for selective binding to diols or other biological targets.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethylsulfonyl)Phenylboronic Acid
CAS No.	1150114-49-0
Molecular Formula	C8H8BF3O4S
Molecular Weight	268.02 g/mol
Synonyms	[2-Methyl-5-(trifluoromethylsulfonyl)phenyl]boronic acid; 2-Methyl-5-(triflyl)phenylboronic acid; 5-(Trifluoromethanesulfonyl)-2-methylbenzeneboronic acid; 2-Methyl-5-((trifluoromethyl)sulfonyl)benzeneboronic acid; Boronic acid, B-[2-methyl-5-[(trifluoromethyl)sulfonyl]phenyl]-; 2-Methyl-5-trifluoromethanesulfonylphenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethylsulfonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.