Description

1-Bromo-4-(Bromomethyl)-2-Methoxybenzene is a versatile and highly functionalized aromatic building block, specifically a benzyl bromide derivative with an additional bromine substituent. This compound is valued for its dual reactive sites, enabling its use in sequential cross-coupling reactions and as a key precursor in complex organic synthesis. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzyl moiety.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromomethyl group facilitates further functionalization.
• Ligand and Catalyst Development: Employed in the preparation of specialized phosphine or nitrogen-based ligands for transition metal catalysis.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and liquid crystals.
• Chemical Research: A valuable reagent in academic and industrial R&D for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Fine Chemical Production: Utilized in the multi-step synthesis of dyes, pigments, and other high-value aromatic compounds.

Basic Information

Product Name	1-Bromo-4-(Bromomethyl)-2-Methoxybenzene
CAS No.	1148110-16-0
Molecular Formula	C8H8Br2O
Molecular Weight	279.96 g/mol
Synonyms	4-Bromo-2-methoxybenzyl bromide; 2-Methoxy-4-bromobenzyl bromide; (4-Bromo-2-methoxyphenyl)methyl bromide; 1-Bromo-4-(bromomethyl)-2-methoxy-benzene; α,4-Dibromo-2-methoxytoluene; 2-Methoxy-α,4-dibromotoluene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(Bromomethyl)-2-Methoxybenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or suitably opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.