Description

3-(3-Bromopropyl)-2,3-Dihydro-2-Oxo-1H-Benzimidazole-1-Carboxylic Acid 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs), particularly in oncology and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical producers requiring a reliable, high-quality building block for complex molecular construction.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzimidazole-derived active pharmaceutical ingredients (APIs).
• Oncology Drug Discovery: Used in research and development of potential chemotherapeutic agents and targeted cancer therapies.
• Protease Inhibitor Synthesis: Serves as a precursor in the creation of protease inhibitors for antiviral and other therapeutic applications.
• Kinase Inhibitor Development: Employed in the construction of kinase inhibitor scaffolds for signal transduction research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Chemical Biology & Proteomics: Utilized in the design of chemical probes and activity-based probes for studying enzyme function.

Basic Information

Item	Details
Product Name	3-(3-Bromopropyl)-2,3-Dihydro-2-Oxo-1H-Benzimidazole-1-Carboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	1148017-48-4
Molecular Formula	C15H19BrN2O3
Molecular Weight	355.23 g/mol
Synonyms	tert-Butyl 3-(3-bromopropyl)-2-oxo-2,3-dihydro-1H-benzimidazole-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-(3-bromopropyl)-2-benzimidazolinone; 3-(3-Bromopropyl)-1-Boc-2-benzimidazolinone; 1-Boc-3-(3-bromopropyl)benzimidazol-2-one; Boc-3-(3-bromopropyl)-2-benzimidazolinone; 2-Oxo-3-(3-bromopropyl)-1H-benzimidazole-1-carboxylic acid tert-butyl ester; 3-(3-Bromopropyl)-2-oxo-2,3-dihydro-1H-benzimidazole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of 3-(3-Bromopropyl)-2,3-Dihydro-2-Oxo-1H-Benzimidazole-1-Carboxylic Acid 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.