Description

1-Benzoyl-2,3-Dihydro-1H-Indole-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-based molecular structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules requiring the indole-2-carboxylic acid framework.
• Biochemical Research: Acts as a reference standard or a starting material for the development of enzyme inhibitors or receptor modulators.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	1-Benzoyl-2,3-Dihydro-1H-Indole-2-Carboxylic Acid
CAS No.	1147550-55-7
Molecular Formula	C16H13NO3
Molecular Weight	267.28 g/mol
Synonyms	2,3-Dihydro-1H-indole-2-carboxylic acid, 1-benzoyl-; 1-Benzoyl-2,3-dihydroindole-2-carboxylic acid; 2-Carboxy-1-benzoyl-2,3-dihydroindole; 1-Benzoylindoline-2-carboxylic acid; Bz-Indoline-2-COOH; 1147550-55-7; (2,3-Dihydro-1H-indol-2-yl)(phenyl)methanone-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Benzoyl-2,3-Dihydro-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.