Description

1-((2-Chloro-4-Morpholinothieno[3,2-D]Pyrimidin-6-Yl)Methyl)-n-Methyl-n-(Tetrahydrofuran-3-Yl)Piperidin-4-Amine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of targeted therapies. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CRMOs), and fine chemical producers focused on oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of novel drug candidates, particularly kinase inhibitors.
• Oncology Research: Used in the synthesis of potential therapeutic agents targeting specific cancer pathways.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Integral component in multi-step synthetic routes for the production of complex target molecules at pilot and commercial scales.
• Biochemical Research: Utilized as a tool compound for probing biological mechanisms and enzyme interactions in vitro.
• Custom Synthesis: Starting material for contract manufacturing organizations (CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	1-((2-Chloro-4-Morpholinothieno[3,2-D]Pyrimidin-6-Yl)Methyl)-n-Methyl-n-(Tetrahydrofuran-3-Yl)Piperidin-4-Amine
CAS No.	1147423-11-7
Molecular Formula	C21H28ClN5O2S
Molecular Weight	457.99 g/mol
Synonyms	1-[(2-Chloro-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-N-methyl-N-(oxolan-3-yl)piperidin-4-amine; 1-((2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)-N-methyl-N-(tetrahydrofuran-3-yl)piperidin-4-amine; 1147423-11-7; UNII-9K4F8V8W4M; 9K4F8V8W4M; Thienopyrimidine derivative; Morpholinothienopyrimidine intermediate; Kinase inhibitor intermediate.
EINECS	Contact for details

Quality Control

Our 1-((2-Chloro-4-Morpholinothieno[3,2-D]Pyrimidin-6-Yl)Methyl)-n-Methyl-n-(Tetrahydrofuran-3-Yl)Piperidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.