Description

1-((2-Chloro-4-Morpholinothieno[3,2-D]Pyrimidin-6-Yl)Methyl)-n-Cyclobutyl-n-Methylpiperidin-4-Amine is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound matters for its role as a key building block in the synthesis of targeted kinase inhibitors, offering researchers a reliable and well-characterized starting material. It is primarily needed by R&D teams and process chemists in the pharmaceutical and biotechnology industries working on oncology and inflammatory disease therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel small-molecule drug candidates.
• Kinase Inhibitor Research: Used as a core scaffold for developing and optimizing potent and selective kinase inhibitors.
• Oncology Drug Discovery: Integral to research programs focused on novel anti-cancer agents targeting specific signaling pathways.
• Process Chemistry & Scale-Up: Provides a defined chemical entity for process development, route scouting, and optimization studies.
• Chemical Biology: Employed in the design of chemical probes to study enzyme function and cellular mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied for custom synthesis projects requiring this specific, complex heterocyclic structure.

Basic Information

Product Name	1-((2-Chloro-4-Morpholinothieno[3,2-D]Pyrimidin-6-Yl)Methyl)-n-Cyclobutyl-n-Methylpiperidin-4-Amine
CAS No.	1147423-09-3
Molecular Formula	C21H28ClN5OS
Molecular Weight	433.99 g/mol
Synonyms	N-Cyclobutyl-N-methyl-1-[(2-chloro-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]piperidin-4-amine; 1-[(2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl]-N-cyclobutyl-N-methylpiperidin-4-amine; UNII-3G8G3K6Q5K; 3G8G3K6Q5K; BDBM50389335; AKOS025310584; ZINC000103486535; Thienopyrimidine derivative 1147423-09-3
EINECS	Contact for details

Quality Control

Our 1-((2-Chloro-4-Morpholinothieno[3,2-D]Pyrimidin-6-Yl)Methyl)-n-Cyclobutyl-n-Methylpiperidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting standards for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is moisture-sensitive; keep the container tightly sealed under inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.