Description

5-Bromo-6-Methylisoquinoline is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized isoquinoline scaffold, which serves as a critical precursor for the development of complex molecules, particularly in pharmaceutical research and material science. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery programs and the synthesis of novel functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the isoquinoline moiety into more complex molecular architectures.
• Ligand Synthesis: Useful for creating novel ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & R&D: A valuable reagent for university and corporate research laboratories exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	5-Bromo-6-Methylisoquinoline
CAS No.	1146298-61-4
Molecular Formula	C10H8BrN
Molecular Weight	222.08 g/mol
Synonyms	6-Methyl-5-bromoisoquinoline; Isoquinoline, 5-bromo-6-methyl-; 5-Bromo-6-methyl-isoquinoline; 5-Bromo-6-methylisoquinoline; 1146298-61-4; 5-Br-6-Me-isoquinoline
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Methylisoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.