Description

(1-Methyl-1H-Indol-3-Yl)(Piperazin-1-Yl)Methanone is a high-purity, synthetic organic compound featuring a unique indole-piperazine hybrid structure. This compound serves as a critical pharmacological building block and advanced intermediate in modern drug discovery programs. It is primarily required by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents targeting central nervous system (CNS) disorders and other disease areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting serotonin and dopamine receptor pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in in vitro assays to study receptor binding affinity and enzyme inhibition for neurological targets.
• Custom Synthesis Building Block: Sourced by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	(1-Methyl-1H-Indol-3-Yl)(Piperazin-1-Yl)Methanone
CAS No.	1146293-65-3
Molecular Formula	C14H17N3O
Molecular Weight	243.31 g/mol
Synonyms	1-(1-Methyl-1H-indole-3-carbonyl)piperazine; 1-Methyl-1H-indole-3-carboxylic acid piperazide; 1-Methylindole-3-carboxylic acid piperazide; N-(Piperazin-1-yl)-1-methyl-1H-indole-3-carboxamide; (1-Methylindol-3-yl)(piperazin-1-yl)methanone; 3-(Piperazine-1-carbonyl)-1-methyl-1H-indole; 1146293-65-3
EINECS	Contact for details

Quality Control

Our (1-Methyl-1H-Indol-3-Yl)(Piperazin-1-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.