Description

1H-Indazole, 3-Ethyl-4-Fluoro- is a high-purity fluorinated indazole derivative, a crucial building block in modern organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecules with enhanced biological activity and specific physicochemical properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom and indazole core can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, heterocyclic structure.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or a tagging reagent in the design of chemical probes for target identification and validation.
• Academic & Contract Research: Essential for methodological development in organic chemistry and medicinal chemistry within university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-Up: A starting material for custom manufacturing organizations (CMOs) to produce kilogram to multi-kilogram quantities for clinical trial material supply.

Basic Information

Product Name	1H-Indazole, 3-Ethyl-4-Fluoro-
CAS No.	1146118-69-5
Molecular Formula	C9H9FN2
Molecular Weight	164.18 g/mol
Synonyms	3-Ethyl-4-fluoro-1H-indazole; 4-Fluoro-3-ethyl-1H-indazole; 1H-Indazole, 4-fluoro-3-ethyl-; 3-Ethyl-4-fluoroindazole; 4-Fluoro-3-ethylindazole; 1146118-69-5; 3-Ethyl-4-fluoro-1H-indazole (CAS 1146118-69-5)
EINECS	Contact for details

Quality Control

Our 1H-Indazole, 3-Ethyl-4-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your regulatory filings and ensures reliable performance in your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.