Description

2-Chloro-1-(3-Nitro-Pyridin-2-Yl)-1H-Benzoimidazole, 98+% C12H7Cln4O2, Mw: 274.67 CAS NO 1146080-68-3 is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of novel therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its bioactive heterocyclic core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists exploring structure-activity relationships (SAR) in new chemical entities.
• API Manufacturing: Employed in the commercial-scale production of active pharmaceutical ingredients requiring this specific benzimidazole-pyridine motif.
• Material Science Research: Investigated as a potential monomer or component in the synthesis of specialty polymers and organic electronic materials.

Basic Information

Product Name	2-Chloro-1-(3-Nitro-Pyridin-2-Yl)-1H-Benzoimidazole
CAS No.	1146080-68-3
Molecular Formula	C12H7ClN4O2
Molecular Weight	274.67 g/mol
Synonyms	2-Chloro-1-(3-nitropyridin-2-yl)-1H-benzimidazole; 1H-Benzimidazole, 2-chloro-1-(3-nitro-2-pyridinyl)-; 2-Chloro-1-(3-nitro-2-pyridinyl)-1H-benzimidazole; 2-(2-Chloro-1H-benzimidazol-1-yl)-3-nitropyridine; 1146080-68-3; Benzimidazole, 2-chloro-1-(3-nitro-2-pyridinyl)-; 2-Chloro-1-(3-nitropyridin-2-yl)benzimidazole
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(3-Nitro-Pyridin-2-Yl)-1H-Benzoimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the purity exceeds 98% and meets the stringent specifications required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.