Description

3-Methyl-6-(trifluoromethyl)-1H-indazole is a high-purity, heterocyclic organic compound featuring a versatile indazole core substituted with a methyl and a trifluoromethyl group. This specific molecular architecture makes it a critical building block in modern pharmaceutical and agrochemical research, particularly for introducing metabolic stability and modulating lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of small-molecule drugs, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the properties of the trifluoromethyl group.
• Material Science: Serves as a precursor for functionalized ligands and organic electronic materials.
• Chemical Biology: Employed as a probe or scaffold in the design of enzyme inhibitors and receptor modulators for biological studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for client-specific molecular construction.

Basic Information

Product Name	3-Methyl-6-(trifluoromethyl)-1H-indazole
CAS No.	1146011-20-2
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	3-Methyl-6-(trifluoromethyl)-1H-indazole; 6-(Trifluoromethyl)-3-methyl-1H-indazole; 1H-Indazole, 3-methyl-6-(trifluoromethyl)-; 3-Methyl-6-trifluoromethylindazole; 3-Methyl-6-trifluoromethyl-1H-indazole; 1146011-20-2
EINECS	Contact for details

Quality Control

Every batch of 3-Methyl-6-(trifluoromethyl)-1H-indazole is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.