Description

(1-Tosyl-1H-Indol-4-Yl)Methanamine is a high-purity, functionalized indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical versatile building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indole scaffold's bioactivity.
• Ligand and Catalyst Development: Serves as a functional handle for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors, dyes, and photoresponsive materials due to its conjugated indole system.
• Chemical Biology Probe Synthesis: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a tosyl-protected indole amine functionality.

Basic Information

Product Name	(1-Tosyl-1H-Indol-4-Yl)Methanamine
CAS No.	1145678-74-5
Molecular Formula	C16H16N2O2S
Molecular Weight	300.38 g/mol
Synonyms	4-(Aminomethyl)-1-tosyl-1H-indole; 1H-Indole-4-methanamine, 1-[(4-methylphenyl)sulfonyl]-; 1-Tosyl-1H-indol-4-ylmethanamine; 4-(Aminomethyl)-1-(p-toluenesulfonyl)indole; 1-(Tosyl)-4-(aminomethyl)indole; 4-Aminomethyl-1-tosylindole; p-Toluenesulfonyl-4-aminomethylindole; (1-Tosylindol-4-yl)methylamine
EINECS	Contact for details

Quality Control

Our (1-Tosyl-1H-Indol-4-Yl)Methanamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of pharmaceutical and research customers globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.