Description

n-[2-(1H-Indol-3-Yl)Ethyl]-1,3-Dioxo-2-[3-(Propan-2-Yloxy)Propyl]-2,3-Dihydro-1H-Isoindole-5-Carboxamide CAS NO 1144461-44-8 is a high-purity, complex organic compound featuring a hybrid molecular architecture that combines indole and isoindole-1,3-dione (phthalimide) moieties. This structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the life sciences sector for the synthesis of novel bioactive molecules. The compound's design facilitates exploration in areas such as enzyme inhibition and receptor modulation.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop novel drug candidates.
• Biochemical Tool Compound: Serves as a precursor or reference standard in biochemical assays and pharmacological studies.
• Organic Synthesis: A versatile synthon for constructing complex heterocyclic frameworks in academic and industrial research laboratories.
• Preclinical Development: Supplied in milligram to kilogram quantities for use in early-stage drug discovery and process chemistry optimization.

Basic Information

Product Name	n-[2-(1H-Indol-3-Yl)Ethyl]-1,3-Dioxo-2-[3-(Propan-2-Yloxy)Propyl]-2,3-Dihydro-1H-Isoindole-5-Carboxamide
CAS No.	1144461-44-8
Molecular Formula	C25H25N3O4
Molecular Weight	431.49 g/mol
Synonyms	5-Carboxamido-N-(2-indol-3-ylethyl)phthalimide isopropyl ether; 2-[3-(Isopropoxy)propyl]-N-[2-(1H-indol-3-yl)ethyl]-1,3-dioxoisoindoline-5-carboxamide; 1,3-Dioxo-2-[3-(propan-2-yloxy)propyl]-N-[2-(1H-indol-3-yl)ethyl]isoindole-5-carboxamide; Isopropyloxypropyl phthalimide indole carboxamide; CAS 1144461-44-8; Phthalimide-indole conjugate; Isoindole-1,3-dione derivative
EINECS	Contact for details

Quality Control

Our n-[2-(2-(1H-Indol-3-yl)ethyl]carbamoyl]isoindoline-1,3-dione derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.